At present, about the nature of the enterprise. Western economists have different views. There is also some debate. Some western economists analyze the nature of the enterprise mainly from the perspective of transaction costs that coase emphasizes. But administrators lost £990 a year compared to full-time employees and the average sales or customer service worker lost £800 a year. The general function of deacetylation with the lysine residues is carried out by HDAC enzymes. Apart from this pair of HDACs there exists another enzyme which performs a similar function. The name with this enzyme is SIRT1 also it removes the acetyl group by way of a very unique mechanism. The end product of this enzyme mediated reaction is nicotinamide. Removal of acetyl group by HDACs doesn't involve NAD+ hydrolysis. Inhibitors like trichostatin A, which show specific action against HDACs don't have any action against SIRT1. The response to variability is a resilient instinct. Elastic instinct (also called the conditioned reflex) is an organism formed in the process of life change with conditions and reflection, under certain conditions unrelated stimulus be signals caused by reflections of the unconditioned stimulus. It is not innate, but the reflection of the organism under certain conditions under certain conditions. Conditioned reflex can make animal learning and memory and non-conditional reflex related, but completely different new reflection activity. The formation of conditioned reflex is the formation or connection of the cerebral cortex, which is based on non-conditioned reflex. With conditioned reflex, animals not only reflect things that have direct physiological meaning, but also those that have indirect physiological significance. Elastic instinct can make animals for the changed things to adjust their instinctive behavior, make it easy to adapt to changes in the environment, thus than rigid instinct has more flexibility and purpose, and the body through the conditioning can not before the arrival of the stimulus itself accordingly reaction, make the body more proactive and initiative. Anyway, elastic instinct is higher biological value of variability of external things more advanced way of ordering reaction, is on the rigid instinct, extension, and the synthesis, make rigid instinct has more purposeful and flexibility