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One of the easiest ways that companies can avoid animal exams are to use items that are already extensively found in human history and also have proven their safety over time. Companies could also depend upon data from natural and synthetic ingredients which are already previously tested on animals. Computer modeling and databases may be used to determine biological properties of ingredients and make risk assessments. If in a very room or building, Claustrophobia sufferers may constantly be checking for doorways and exits or standing near exits even during large rooms, and feeling fear when doors are closed. Smalls spaces like cars, planes and lifts ca also bring anxious feelings. In some cases being in these situations can bring on panic disorder, in extreme cases just going to a closed door may cause a Panic Attack. ch_sid="A1_550x250_No1";