Langer-Giedion Syndrome can be a true contiguous gene deletion syndrome a result of deletions in the the TRPS and EXT1 genes. The lack of a functional EXT1 gene causes the bone exostoses, bone anomalies and facial abnormalities which can be affecting patients. The EXT1 gene as well as the TRPS1 gene are both absent in patients and research suggests that other genes based in the 8q24.11-8q24.13 region of chromosome 8 might be deleted or non-functional also. Longer deletions in this region are seen as mental retardation as well as the other variations in symptoms stated earlier. Getting All the Above If you are trying to receive benefits when you are mentally ill, documentation of the condition is essential. You need letters and reports about your behavior from family, friends, and also former employers. Their observations as well as a report from a doctor (preferably a psychiatrist or psychologist) who's been treating in your case for long periods of your time are key to getting approved. You have to prove your illness is severe enough to help keep you against working and functioning in daily life.