This gland usually concerning the size a pea. It is located in the brain's base just below the hypothalamus. It is considered the king of the endocrine system. This 'master gland", as it is known, produces hormones that handle controlling a great many other endocrine glands. Seasonal changes, emotions and a number of other facts influence the secretion and output of pituitary hormones. This is done with the brain sensing information and so the hypothalamus providing these details on the pituitary. The pituitary is two parts: the posterior lobe along with the anterior lobe. The anterior lobe regulates adrenal, thyroid and reproductive gland activity. It also creates a various hormones, such as prolactin, corticotropin, growth hormones and thyrotropin. Endorphins are also secreted by this gland, and yes it controls a female's menstrual period and ovulation. The posterior lobe releases the antidiuretic hormone and this is responsible for controlling water balance by the body processes. It also produces oxytocin, which is responsible for stimulating contractions during childbirth. Langer-Giedion Syndrome is often a true contiguous gene deletion syndrome due to deletions both in the TRPS and EXT1 genes. The lack of a functional EXT1 gene causes the bone exostoses, bone anomalies and facial abnormalities which can be noticed in patients. The EXT1 gene and the TRPS1 gene tend to be absent in patients and research suggests that other genes based in the 8q24.11-8q24.13 region of chromosome 8 may be deleted or non-functional also. Longer deletions in this area are characterized by mental retardation and also the other variations in symptoms stated previously. A company called AliveMax has come up with a solution to this problem by creating a range of nutritional sprays that mean you can spray your daily dose of the essential nutrients your body needs to stay healthy directly into your mouth. Alive Max claim that their proprietary vortex technology increases the bio-availability of the nutrients with up to 98% absorption rate.