Langer-Giedion Syndrome can be a true contiguous gene deletion syndrome a result of deletions in the the TRPS and EXT1 genes. The lack of a functional EXT1 gene causes the bone exostoses, bone anomalies and facial abnormalities which can be affecting patients. The EXT1 gene as well as the TRPS1 gene are both absent in patients and research suggests that other genes based in the 8q24.11-8q24.13 region of chromosome 8 might be deleted or non-functional also. Longer deletions in this region are seen as mental retardation as well as the other variations in symptoms stated earlier. First though, I want to make it precise that there actually is no "one way" to film a makeup tutorial. If you've checked out the zillions of tutorials on the market online you will find such variety, many of which are sooo informative and quite entertaining too! And yeah, some might use a facelift, no pun intended lol! And apart from showing you the places you really want to check out - those who will not increase the risk for guidebooks - they're going to coach you on about Thai customs, traditions and the way you should conduct yourself when visiting certain establishments. Thai culture differs greatly from your west so it will be important to know and understand how to behave in order not offend anyone.