Non-steroidal anti-inflammatory drugs (non-steroidal anti-inflammatory drugs): can reduce pain and inflammation. Over-the-counter NSAIDs include ibuprofen (Advair, Motolin IB) and naproxen sodium (Aleve). Some non-steroidal anti-inflammatory drugs can be used as creams, gels or patches that can be applied to specific joints. Lack of sleep builds stress and lowers testosterone in your body.