Ruth Purple is a successful Relationship Coach who has been helping and coaching individuals and couples for many years. When the body makes too little estrogen, method . 'estrogen deficiency." Symptoms of estrogen deficiency are the usual signs of menopause, including vaginal dryness, nigh sweats, hot flashes, painful intercourse, and depression (Lee). These symptoms are mild in menopausal women, and when mild, require no treatment, they're not normal for younger women and may be reported to a health care provider.