Silagra, which contains Sildenafil Citrate, acts on the specific enzyme to advertise erection. A particular enzyme called as phosphodiesterase type five is dramatically reduced after the intake of Sildenafil Citrate. Reduction in PDE5 level boosts the chemicals ' Nitric Oxide and cyclic Guanosine Monophosphate ' so that you can raise the flow of blood during the entire system, such as the penile organ. Eventually, enough blood is supplied on the spongy erectile tissues to generate the penile shaft firm for satisfactory coital session. The effect on this medicine is approximately six hours; hence, men can experience erections on sexual stimulation for the reason that specific duration. This can means that sudden ceasing curative measures on the onset of physical relief may lead to the recurrence and persistence of the infection. It most often develops in adults over the age of 40. It is also more common in women and in people with a family history. However, it can occur at any age due to injury or other joint-related diseases such as gout or rheumatoid arthritis.