Langer-Giedion Syndrome can be a true contiguous gene deletion syndrome a result of deletions in the the TRPS and EXT1 genes. The lack of a functional EXT1 gene causes the bone exostoses, bone anomalies and facial abnormalities which can be affecting patients. The EXT1 gene as well as the TRPS1 gene are both absent in patients and research suggests that other genes based in the 8q24.11-8q24.13 region of chromosome 8 might be deleted or non-functional also. Longer deletions in this region are seen as mental retardation as well as the other variations in symptoms stated earlier. If You Don't Care Which Gender You Get, Having Sex Often When Trying To Conceive Is A Decent Idea: The reasoning behind this method makes a large amount of sense. You only have a small window of time month after month when it's possible to actually get pregnant. So, your odds are already limited. Each time you have intercourse, more sperm is released which creates more chances that you should actually conceive. It only is smart that you would like to provide yourself as numerous chances for fulfillment as you can. Having intercourse typically as is possible is one way to achieve this. But consultation is not the end all and be all of the treatment, adherence to the therapeutic regimen is of utmost importance. The black-tie awards ceremony was held on 15 June at the Royal Armouries in Leeds, at the centre of the country’s great east-west glass manufacturing corridor – where nine out of ten of the UK’s largest glass manufacturers have production sites.