Langer-Giedion Syndrome can be a true contiguous gene deletion syndrome a result of deletions in the the TRPS and EXT1 genes. The lack of a functional EXT1 gene causes the bone exostoses, bone anomalies and facial abnormalities which can be affecting patients. The EXT1 gene as well as the TRPS1 gene are both absent in patients and research suggests that other genes based in the 8q24.11-8q24.13 region of chromosome 8 might be deleted or non-functional also. Longer deletions in this region are seen as mental retardation as well as the other variations in symptoms stated earlier. Building chiseled 6-pack abs is on the top of their list for a lot of guys. The problem is that revealing those hard worked 6-pack abs beneath a layer of fat can seem just like an impossible task. You can do as much ab exercises as you like, starve yourself or spend hours on the treadmill hoping of revealing your six pack but unless you follow these top 10 secrets below you'll never be in a position to reveal your 6-pack abs. Combining L-Argentine with the tree bark Pycnogenol has observed about a 90% enhance in male libido in latest reports. The best way to prevent this from happening is to re-think your views about it