Ankylosing spondylitis - a long-term inflammation that affects mainly the spine's bones, muscles and ligaments, resulting in stiff and joint fusion. Other problems may include swelling of tendons, eyes and joints. For tthis chapter you'll want to complete the next objectives: setup office upstairs, hire staff, perform centerfold shoot, build a magazine and meet Jak. Sounds easy right? Well chapter 1 is actually the sport tutorial and you'll be assisted because of your in-staff when you do the hiring and firiing.You'll be assisted bu Julie McCollough and can demonstrate the ropes. A Playboy bunny, Victoria Fuller will show you the ropes in conversations. Try practicing on Julie - before too long Dick your Chief of Staff will cue you in on things and get you to go upstairs. From there you need to start getting a journalist. Pick on which includes the most effective stats at the moment and just keep coming back to find better prospects. But you can't engage a journalist without having a staff desk so get one now. (2 pt reward). The vast majority of patients who develop this arthropathy have diabetes mellitus. Specifically these patients have diabetic peripheral neuropathy. The incidence inside diabetic human population is about 8.5 per 1000 patients. There are approximately sixteen million diagnosed and undiagnosed diabetics within the United States population; and another approximately forty million individuals with impaired glucose tolerance which makes them predisposed to diabetes mellitus.