The vast majority of patients who develop this arthropathy have diabetes mellitus. Specifically these patients have diabetic peripheral neuropathy. The incidence inside diabetic human population is about 8.5 per 1000 patients. There are approximately sixteen million diagnosed and undiagnosed diabetics within the United States population; and another approximately forty million individuals with impaired glucose tolerance which makes them predisposed to diabetes mellitus. It most often develops in adults over the age of 40. It is also more common in women and in people with a family history. However, it can occur at any age due to injury or other joint-related diseases such as gout or rheumatoid arthritis. According to the Centers for Disease Control and Prevention (CDC), 54.4 million adults in the United States have undergone some form of arthritis diagnosis. Among these people, 23.7 million people have been somewhat limited in their activities.