Alarms have been raised, however, regarding dangers related to hormone replacement therapy (HRT). These risks have been found in connection with what is known as commercial HRT. Possible side effects include thrombosis or blood clots, lowered glucose tolerance, migraine headaches, vision problems, acne, depression and bloating. Women have been known to experience breast tenderness, too. “We’re obviously delighted to be featured in Love Your Home and Garden. It’s very pleasing to be recognised as a leading provider of aluminium windows and doors – but it’s just as satisfying to be supporting good people going through hard times. 1. Avoid (HRT) Hormone Replacement Therapy. Synthetic HRT boosts the risk of Breast Cancer. In 2002, a huge double blind placebo study called ?Women?s Health Initiative? sponsored from the World Health Organization (WHO) was stopped early since it was proven in the study that HRT causes breast cancer.