The person who suffers from this complaint features a problems in which the glucose content in the blood is too high. This situation occurs because the body's either not able to produce enough insulin, produce no insulin, or has cells that does not answer the insulin the pancreas produces. As a result, an excessive amount of sugar builds in the blood. The excess blood sugar passes from the body through urine. So, although the blood has plenty of glucose, cellular structure didn't get the glucose for that element energy and growth. Identical twins originate from one particular egg that's been fertilized by one sperm. For unknown reasons, the fertilized egg splits into 2 or more embryos during the first stage of development. Some identical twins share the same placenta. However, they generally grow within separate amniotic sacs inside the uterus. In rare cases, identical twins share one amniotic sac (monoamniotic). The vast majority of patients who develop this arthropathy have diabetes mellitus. Specifically these patients have diabetic peripheral neuropathy. The incidence inside diabetic human population is about 8.5 per 1000 patients. There are approximately sixteen million diagnosed and undiagnosed diabetics within the United States population; and another approximately forty million individuals with impaired glucose tolerance which makes them predisposed to diabetes mellitus.