The person who has this complaint has a condition in that the glucose content within the blood is too high. This situation occurs as the is either not able to produce enough insulin, produce no insulin, or has cells that will not react to the insulin the pancreas produces. As a result, a lot of sugar builds up within the blood. The excess blood glucose levels passes out of the body through urine. So, although the blood has plenty of glucose, cells didn't obtain the glucose to the element energy and growth. Serious loss of cartilage can cause the bones to rub over the bones, changing the shape of the joints, forcing the bones out of their normal position.