Testosterone 4. Sleep. Take enough sleep. This is the natural way to increase libido. Low libido often is a result of inadequate sleep. Your adrenal glands may be really starred and need some rest. Alarms have been raised, however, regarding dangers related to hormone replacement therapy (HRT). These risks have been found in connection with what is known as commercial HRT. Possible side effects include thrombosis or blood clots, lowered glucose tolerance, migraine headaches, vision problems, acne, depression and bloating. Women have been known to experience breast tenderness, too.