Serious loss of cartilage can cause the bones to rub over the bones, changing the shape of the joints, forcing the bones out of their normal position. Analgesics: These relieve pain, but have no effect on inflammation. Examples include Tylenol, Ultram, and Vicodin, Lortab, which contain Oxycontin or hydrocodone. An increasing number of everyone has discovered their entrepreneurial spirits since downturn in the economy that began around 2008. Massive lay-offs and closed businesses inflated the unemployment figures to "historic proportions" as outlined by multiple news sources. Any relatively scarce job openings typically become inundated with applicants, creating highly competitive situations. Rising costs of gas and related commuting expenses only enhance the stress of finding and looking after regular employment. 1. Work Hard and Rest Harder